Texas Woman's University was founded in 1901 in Denton, Texas, as the Texas Industrial Institute and College for the Education of White Girls of the State of Texas in the Arts and Sciences; the current name dates to 1957. It began the first nationally accredited nursing program, affiliated with Dallas' Parkland Hospital, in Texas in 1950 and began awarding doctorates in 1953. It became integrated in 1961 and coeducational in 1994. The health science and nursing programs have additional campuses in Dallas and Houston.

The Faculty Wives was established in 1973-1974 when the medical school was new to the Medical Center “to promote friendship among its members and to be of service to the Medical School and the community”. A 1978 bake sale started the scholarship fund. In addition to scholarships and book money, the organization has donated to many institutions and programs. Female faculty were admitted as of the 1985-1986 school year.

The Woman’s Hospital of Texas was founded in 1976 and specializes in care focused on the needs of women.