Ruth SoRelle was born in Port Arthur on October 9, 1948. She is known for her work in medical and science writing in Houston. The bulk of the papers cover the decades from 1980 to 2015. She worked at the Houston Chronicle where she covered the AIDS/HIV epidemic in Houston. She also worked at Baylor College of Medicine where her last position before retirement was as chief science editor in the Office of Vice President of Public Affairs. She retired December 31, 2015, although she continues to write. The collection includes photos, plaques, framed objects, clipping books, clipping files, reference and topic files, childhood writings, science and medical articles, reporter notebooks, and clippings from SoRelle's budding career as a journalist at the University of Texas. One notable area of interest are the articles related to the HIV/AIDS epidemic in Houston. These article document the early evidence of the disease in Houston. The collection is in good condition, although some of the news clips are showing signs of degradation from the acid in the newspaper. There are 13 boxes (13 cubic feet).

The Ferid Murad, MD papers consists of fifiteen handwritten notebooks documenting Dr. Ferid Murad's research. The notebooks include research data presented in tables and charts, as well as Dr. Murad's notes. The notebooks span the years 1959-1970. The first set of notebooks (#1-12) corresponds to his doctoral and medical studies at Western Reserve University, which concluded in 1965. The second set (1-11) pick up in 1967.

In addition, the collection includes a small number of printed materials from organizations of which Dr. Murad was a part. Notably, there are manuals from his internship and residency at Massachusetts General Hospital, dating around 1965. The Information for House Staff manual includes handwritten notes. The only two items dating from after 1970 are are a guide from the Stanford Institute of Biological and Clinical Investigation and a National Academy of Sciences membership directory.

The Elwin L. Shelton, Jr., MD papers consists largely of materials related to his professional life, such as presentations and publications, published and unpublished papers, and accreditations. There are copies of Medical Director's Notebook from 1957-1960. There are also materials on topics such as philosophy, hypnosis, intestinal by-pass, GI, breast, and peritoneal dialysis research. Some items pertain to the Texas Surgical Society, Southern Society of Clinical Surgeons, and Houston Gastroenterological Society. Finally, there are some personal items, such as biographical data, photos and "treasured letters." The collection ranges in dates from 1948-1990.