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The notebooks from Dr. Knobil's research laboratories comprise the largest series (X). General Files, Series IV, contains material including correspondence, lectures and speeches from the early 1980s to 2000. It was retained in the alphabetical order it was received. Material in Series II was labeled Harvard and deals primarily with Dr. Knobil's tenure at Harvard University in the 1950s. Material about his Deanship of the University of Texas Medical School at Houston can be found in Series III and IV.

The Ferid Murad, MD papers consists of fifiteen handwritten notebooks documenting Dr. Ferid Murad's research. The notebooks include research data presented in tables and charts, as well as Dr. Murad's notes. The notebooks span the years 1959-1970. The first set of notebooks (#1-12) corresponds to his doctoral and medical studies at Western Reserve University, which concluded in 1965. The second set (1-11) pick up in 1967.

In addition, the collection includes a small number of printed materials from organizations of which Dr. Murad was a part. Notably, there are manuals from his internship and residency at Massachusetts General Hospital, dating around 1965. The Information for House Staff manual includes handwritten notes. The only two items dating from after 1970 are are a guide from the Stanford Institute of Biological and Clinical Investigation and a National Academy of Sciences membership directory.