Sigma Xi: The Scientific Research Honor Society is a medical honor society, founded in 1886 at Cornell University. Membership is by invitation based on achievements and potential. Sigma Xi supports research grants and other programs in medical and science education. The Rice University/Texas Medical Center chapter was founded in 1938. It was evidently inactive for a few years in the late 1950s and early 1960s until an effort was made in 1962 to revitalize it; the materials in this collection date from around that time forward.